Recombinant Human HSPB8/HSP22 Protein

Product Discontinued

Recombinant Human HSPB8/HSP22 Protein Summary

• Description: HSPB8 (Human) Recombinant Protein
  
  Source: E. coli
  
  Amino Acid Sequence:
• Preparation Method: Escherichia coli expression system
• Details of Functionality: Immunoreactivity is confirmed by reaction with monoclonal mouse antibodies against HSP-22.
• Protein/Peptide Type: Recombinant Protein
• Gene: HSPB8

Applications/Dilutions

• Dilutions:
  • Functional
  • SDS-Page
• Application Notes: This product is useful for and SDS-PAGE and Functional assays.

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: No additive Reconstitute with deionized water.
• Preservative: No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human HSPB8/HSP22 Protein

• Alpha-crystallin C chain
• CMT2L
• CRYAC
• DHMN2
• E2IG1
• E2IG1E2-induced gene 1 protein
• H11
• H11DHMN2
• heat shock 22kDa protein 8
• heat shock 27kDa protein 8
• heat shock protein beta-8
• HMN2
• HMN2A
• HSP22
• HSP22CMT2L
• HSPB8
• Protein kinase H11
• Small stress protein-like protein HSP22

Background

HSP22 is encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HSPB8