Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, KD
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
HSP22 is encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Bioinformatics
Entrez |
Human Mouse |
Uniprot |
Human Human Human Human Human Human Human |
Product By Gene ID |
26353 |
Alternate Names |
- CRYAC
- Protein kinase H11
- heat shock protein beta-8
- Alpha-crystallin C chain
- HMN2
- HspB8
- HMN2A
- heat shock 27kDa protein 8
- H11DHMN2
- HSP22CMT2L
- E2IG1E2-induced gene 1 protein
- Small stress protein-like protein HSP22
- heat shock 22kDa protein 8
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Research Areas for HSPB8/HSP22
Find related products by research area and learn more about each of the different research areas below.
Protein Kinase
Bioinformatics Tool for HSPB8/HSP22
Discover related pathways, diseases and genes to HSPB8/HSP22. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.