HSPB8/HSP22 Products

Description

HSP22 is encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Bioinformatics

Entrez	26353 Human 62353 Mouse
Uniprot	AAH02673 Human AAH02673.1 Human NM_014365 Human NP_055180 Human NP_055180.1 Human Q9UJY1 Human Q9UJY2 Human
Product By Gene ID	26353
Alternate Names	Alpha-crystallin C chain CRYAC E2IG1E2-induced gene 1 protein H11DHMN2 heat shock 22kDa protein 8 heat shock 27kDa protein 8 heat shock protein beta-8 HMN2 HMN2A HSP22CMT2L HspB8 Protein kinase H11 Small stress protein-like protein HSP22

Research Areas for HSPB8/HSP22

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase