HOXA4 Antibody

Product Discontinued

HOXA4 Antibody Summary

• Immunogen: Peptide with sequence C-DQGPAGPKGKEP corresponding to internal region according to Uniprot Mouse NP_032291.1.
• Epitope: C-DQGPAGPKGKEP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: HOXA4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:2000
• Application Notes: WB: Preliminary experiments gave an approx. 26 kDa band in mouse colon lysates after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 30.5 kDa band according to NP_032291.1. The 26 kDa band was successfully blocked by incubation with the immunizing peptide.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for HOXA4 Antibody

• homeo box A4
• homeobox A4
• Homeobox protein Hox-1.4
• Homeobox protein Hox-1D
• homeobox protein Hox-A4
• HOX1
• Hox-1.4-like protein
• HOX1DDfd-like protein

Background

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HOXA4 Antibody (NBP1-52165)(1)

Publication using NBP1-52165

• Klausen C, Leung PC, Auersperg N. Cell motility and spreading are suppressed by HOXA4 in ovarian cancer cells: possible involvement of beta1 integrin. Mol Cancer Res 2009-09-01 [PMID: 19723874]

Bioinformatics

• Gene Symbol: HOXA4
• Entrez:
  • 15401(Mouse)
• Uniprot:
  • NP_032291.1(Mouse)