GRK6 Antibody (8D4) - Azide and BSA Free

Western Blot: GRK6 Antibody (8D4) [H00002870-M10] - Analysis of GRK6 expression in Jurkat (Cat # L017V1).

ELISA: GRK6 Antibody (8D4) [H00002870-M10] - Detection limit for recombinant GST tagged GRK6 is approximately 0.3ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 8D4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

GRK6 Antibody (8D4) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: GRK6 (AAH17272, 71 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. CATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRF
• Specificity: GRK6 - G protein-coupled receptor kinase 6
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: GRK6
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for GRK6 Antibody (8D4) - Azide and BSA Free

• EC 2.7.11
• EC 2.7.11.16
• FLJ32135
• G protein-coupled receptor kinase 6
• GPRK6G protein-coupled receptor kinase GRK6

Background

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GRK6 Antibody (H00002870-M10)(1)

Publication using H00002870-M10

• McCormick PJ, Segarra M, Gasperini P et al. Impaired Recruitment of Grk6 and beta-Arrestin2 Causes Delayed Internalization and Desensitization of a WHIM Syndrome-Associated CXCR4 Mutant Receptor. PLoS One. 2009-12-01 [PMID: 19956569]

Bioinformatics

• Gene Symbol: GRK6
• Entrez:
  • 2870(Human)
• OMIM:
  • 600869(Human)
• Uniprot:
  • AAH17272(Human)