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GPRC5B Antibody

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Immunohistochemistry-Paraffin: GPRC5B Antibody [NLS413] - IHC analysis of Brain, Neurons and glia using NLS413 at 3 ug/ ml.
Immunohistochemistry-Paraffin: GPRC5B Antibody [NLS413] - IHC analysis of Brain, Neurons and glia using NLS413 at 3 ug/ ml.

Product Details

Summary
Reactivity Hu, Mk, PmSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

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GPRC5B Antibody Summary

Immunogen
Synthetic 20 amino acid peptide from C-terminus of human GPRC5B.
Epitope
C-terminal domain of human
Specificity
Human GPRC5B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GPRC5B
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 4 ug/ml to 22 ug/ml
Positive Control
GPRC5B Lysate (NBL1-11304)

Reactivity Notes

Gorilla, Orangutan, Marmoset. Predicted cross-reactivity based on sequence identity: Mouse (85%), Rat (85%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GPRC5B Antibody

  • G protein-coupled receptor, family C, group 1, member B
  • G protein-coupled receptor, family C, group 5, member B
  • GPRC5B
  • RAIG2
  • RAIG-2A-69G12.1
  • RAIG2G-protein coupled receptor family C group 5 member B
  • retinoic acid responsive gene protein
  • Retinoic acid-induced gene 2 protein

Background

GPRC5B is an Orphan-C GPCR induced by retinoids. GPRC5B shows some homologies to the metabotropic glutamate receptor-like family of GPCRs; however, the GPRC5B protein has a short N-terminal domain compared to other family C members. GPRC5B expression is reported to be widespread with highest levels observed in brain, kidney, pancreas and testis. ESTs have been isolated from a wide variety of human tissue libraries, including normal adrenal, brain, heart/melanocyte/uterus and pineal, and cancerous germ cell, nerve, ovary and parathyroid.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Positive Control Lysate(s)

GPRC5B Overexpression Lysate (Native)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GPRC5B
Entrez