GPRC5B Antibody

Immunohistochemistry-Paraffin: GPRC5B Antibody [NLS412] - Analysis of anti-GPRC5B antibody with human brain, neurons and glia.

Product Discontinued

GPRC5B Antibody Summary

• Immunogen: Synthetic 20 amino acid peptide from C-terminus of human GPRC5B.
• Epitope: C-terminal domain of human
• Specificity: Human GPRC5B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Canine (90%), Primate (95%), Turkey (90%), Equine (90%), Bovine (90%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GPRC5B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 4 - 19 ug/ml
• Control:

  GPRC5B Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Orangutan (95%), Panda (90%), Porcine (85%), Opossum (85%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GPRC5B Antibody

• G protein-coupled receptor, family C, group 1, member B
• G protein-coupled receptor, family C, group 5, member B
• GPRC5B
• RAIG2
• RAIG-2A-69G12.1
• RAIG2G-protein coupled receptor family C group 5 member B
• retinoic acid responsive gene protein
• Retinoic acid-induced gene 2 protein

Background

GPRC5B is an Orphan-C GPCR induced by retinoids. GPRC5B shows some homologies to the metabotropic glutamate receptor-like family of GPCRs; however, the GPRC5B protein has a short N-terminal domain compared to other family C members. GPRC5B expression is reported to be widespread with highest levels observed in brain, kidney, pancreas and testis. ESTs have been isolated from a wide variety of human tissue libraries, including normal adrenal, brain, heart/melanocyte/uterus and pineal, and cancerous germ cell, nerve, ovary and parathyroid.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPRC5B
• Entrez:
  • 51704(Human)