GPR50 Antibody

Immunohistochemistry-Paraffin: GPR50 Antibody [NLS6621] - Analysis of anti-GPR50 antibody with human pituitary.

Product Discontinued

GPR50 Antibody Summary

• Immunogen: Synthetic 20 amino acid peptide from C-terminus of human GPR50.
• Localization: Cell Membrane
• Specificity: Human GPR50. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GPR50
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 3 - 28 ug/ml
  • Western Blot 1:100 1:2000

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (90%), Gibbon (85%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GPR50 Antibody

• G protein-coupled receptor 50H9Mel1c
• GPR50
• H9
• melatonin-related receptor
• MGC125342
• MTR1L

Background

Melatonin-related receptor is an Orphan-A GPCR with an unknown ligand. The receptor is related to high-affinity melatonin receptors, yet it is unable to bind the melatonin hormone. Melatonin-related receptor expression has been documented from human CNS tissues, specifically in hypothalamus and pituitary, but not in human peripheral tissues. In animals, expression has also been seen in the CNS, and peripheral tissues including adrenal, heart, kidney, lung, skin, intestine, stomach, and testis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPR50
• Entrez:
  • 9248(Human)