gamma-Synuclein Antibody (514304R) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: WB, IHC, ICC/IF
• Clone: 514304R
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

gamma-Synuclein Antibody (514304R) [Alexa Fluor® 647] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: E. coli-derived recombinant human γ-Synuclein
  Asn47-Glu120
  Accession # Q6FHG5
• Specificity: Detects human gamma -Synuclein in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for gamma-Synuclein Antibody (514304R) [Alexa Fluor® 647]

• BCSG1
• BCSG1PERSYN
• Breast cancer-specific gene 1 protein
• gamma-Synuclein
• persyn
• PRSN
• SNCG
• SRPRSN
• Synoretin
• synuclein, gamma (breast cancer-specific protein 1)
• Synuclein-gamma

Background

gamma -Synuclein (SNCG), also called persyn or synoretin, is a 17 kDa, 127 amino acid (aa) cytoplasmic phosphoprotein. It is a member of a family of small, highly conserved synuclein proteins localized predominantly in presynaptic nerve terminals in the brain. SNCG and other synucleins are implicated in neurodegenerative diseases including Parkinson's disease. SNCG expression is elevated in many cancers and is implicated in tumor progression, invasion and proliferation. Within the region used as an immunogen, human SNCG shares 82% and 78% aa identity with mouse and rat SNCG, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.