GALNT12 Antibody [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 450 SE

GALNT12 Antibody [mFluor Violet 450 SE] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human GALNT12 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GALNT12
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for GALNT12 Antibody [mFluor Violet 450 SE]

• colorectal cancer, susceptibility to 1
• CRCS1
• EC 2.4.1.41
• FLJ21212
• GalNAc-T12
• GALNT12
• Polypeptide GalNAc transferase 12
• polypeptide N-acetylgalactosaminyltransferase 12
• Pp-GaNTase 12
• Protein-UDP acetylgalactosaminyltransferase 12
• UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase
• UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12
• UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 12 (GalNAc-T12)

Background

GALNT12, also known as Polypeptide N-acetylgalactosaminyltransferase 12, has a 581 amino acid long isoform that is 67 kDa and a short 272 amino acid isoform that is 32 kDa, plays role in catalyzing the initial reaction in O-linked oligosaccharide biosynthesis, and the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor; displays activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, Gal-NAc-Muc5AC glycopeptide; and initializes mucin-type oligosaccharide biosynthesis in digestive organs. Studies on this protein have shown a relationship with the following disorders and diseases: colorectal cancer, colon cancer, cerebritis, thyroiditis, and prostatitis. This protein has also been shown to have interactions with MUC7, MUC1, MUC2, MUC5AC, and C1GALT1 in the pathways such as the O-linked glycosylation of mucins, metabolism of proteins, post-translational protein modification, and mucin type O-Glycan biosynthesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GALNT12