FPRL2/FPR3 Antibody (374822) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: 374822
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

FPRL2/FPR3 Antibody (374822) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: HEK293 human embryonic kidney cell line transfected with human FPRL2
  Met1-Met352
  Accession # P25089
• Specificity: Detects human FPRL2. Stains human FPRL2 transfectants but not irrelevant transfectants.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: FPR3
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for FPRL2/FPR3 Antibody (374822) [CoraFluor™ 1]

• FMLP-R-II
• FMLPY
• formyl peptide receptor 3
• Formyl peptide receptor-like 2FMLP-related receptor II
• FPR3
• FPRH1
• FPRH1FPRH2
• FPRH2
• FPRL2
• FPRL2FML2_HUMAN
• N-formyl peptide receptor 3
• RMLP-R-I

Background

FPRL2 is a Chemoattractant Receptor involved in the transduction of signals in myeloid cells. Although it is structurally homologous to FPRL1, human FPRL2 does not recognize the N-formylmethionyl peptides (FMLP) as ligands and is not expressed in neutrophils.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FPR3