Flamingo homolog 1/CELSR3 Antibody (2F7)

ELISA: Flamingo homolog 1/CELSR3 Antibody (2F7) [H00001951-M01] - Detection limit for recombinant GST tagged CELSR3 is approximately 0.03ng/ml as a capture antibody.

Product Discontinued

Flamingo homolog 1/CELSR3 Antibody (2F7) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: CELSR3 (NP_001398, 71 a.a. ~ 180 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. REDGGPGLGVREPIFVGLRGRRQSARNSRGPPEQPNEELGIEHGVQPLGSRERETGQGPGSVLYWRPEVSSCGRTGPLQRGSLSPGALSSGVPGSGNSSPLPSDFLIRHH
• Specificity: CELSR3 - cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CELSR3
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Flamingo homolog 1/CELSR3 Antibody (2F7)

• Cadherin family member 11
• cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
• CDHF11
• CDHF11RESDA1
• CELSR3
• EGFL1
• EGFL1cadherin EGF LAG seven-pass G-type receptor 3
• EGF-like protein 1
• EGF-like-domain, multiple 1
• epidermal growth factor-like 1
• Epidermal growth factor-like protein 1
• Flamingo homolog 1
• FMI1anchor protein
• HFMI1
• KIAA0812
• MEGF2
• MEGF2cadherin EGF LAG seven-pass G-type receptor 3, flamingo (Drosophila) homolog
• multiple EGF-like domains 2
• Multiple EGF-like domains protein 2
• Multiple epidermal growth factor-like domains protein 2
• RESDA1

Background

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CELSR3
• Entrez:
  • 1951(Human)
• OMIM:
  • 604264(Human)
• Uniprot:
  • NP_001398(Human)