FKTN Antibody (SR1900) - BSA Free

Western Blot: FKTN Antibody (SR1900) [NBP3-22461] - Western blot analysis using NBP3-22461 in HeLa cell lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: SR1900
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

FKTN Antibody (SR1900) - BSA Free Summary

• Description: Novus Biologicals Rabbit FKTN Antibody (SR1900) - BSA Free (NBP3-22461) is a recombinant monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human FKTN (Uniprot #: O75072)
• Specificity: Detects endogenous levels of total FKTN
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: FKTN
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 51 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for FKTN Antibody (SR1900) - BSA Free

• CMD1X
• EC 2.-
• FCMDMGC134945
• fukutin
• Fukuyama type congenital muscular dystrophy (fukutin)
• Fukuyama type congenital muscular dystrophy protein
• Fukuyama-type congenital muscular dystrophy protein
• LGMD2MMGC134944
• MDDGA4
• MDDGB4
• MDDGC4
• MGC126857
• MGC138243

Background

FKTN genes encode fukutin proteins that in isoform 1 are 461 amino acids long at 54 kDA and at isoform 2 are 430 amino acids long at 49 kDA. These proteins are thought to participate in glycosylation of alpha-dystroglycan/DAG1 as it is probably a glycosyltransferase. Additionally, it may reinforce large a complex surrounding the outside and inside of muscle membranes, further enhancing brain development. FKTN is involved with the CNBP gene. Defects in this gene cause myscular dystrophy-dystroglycanopathy congenital types A4, B4, C4, and cadiomyopathy dilated type 1X. FKTN is also linked to optic atrophy, cleft lip, walker-warburg syndrome, dubowitz syndrome, retinal detachment, and neuronal migration disorders.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FKTN