FBXW12 Antibody

Product Discontinued

FBXW12 Antibody Summary

• Immunogen: FBXW12 (1 a.a. ~ 445 a.a) full-length human protein.MSPTHQIQDPKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSDP
• Specificity: FBXW12 - F-box and WD-40 domain protein 12,
• Clonality: Polyclonal
• Host: Mouse
• Gene: FBXW12
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: This antibody is in antisera and the concentration is unavailable.
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for FBXW12 Antibody

• F-box and WD repeat domain containing 12
• F-box and WD-40 domain-containing protein 12
• F-box- and WD40-repeat-containing protein
• F-box only protein 35MGC120386
• F-box/WD repeat-containing protein 12
• Fbw12
• FBW12MGC120387
• FBXO12FBXO35F-box and WD-40 domain protein 12
• MGC120385

Background

Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FBXW12
• Entrez:
  • 285231(Human)
• Uniprot:
  • AAI01306.1(Human)