FBXW12 Products

Description

Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM]

Bioinformatics

Entrez	285231 Human
Uniprot	AAI01306.1 Human
Product By Gene ID	285231
Alternate Names	F-box and WD repeat domain containing 12 F-box and WD-40 domain-containing protein 12 F-box- and WD40-repeat-containing protein F-box only protein 35MGC120386 F-box/WD repeat-containing protein 12 Fbw12 FBW12MGC120387 FBXO12FBXO35F-box and WD-40 domain protein 12 MGC120385