FAM3C Antibody (Delphy-1) - BSA Free

Product Discontinued

FAM3C Antibody (Delphy-1) - BSA Free Summary

• Immunogen: Recombinant human ILEI (aa 42-227).
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: FAM3C
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunoprecipitation 1:100
  • Western Blot 1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for FAM3C Antibody (Delphy-1) - BSA Free

• D6WSU176e
• FAM3C
• family with sequence similarity 3, member C
• GS3876
• ILEI
• ILEIInterleukin-like EMT inducer
• predicted osteoblast protein

Background

In 2006, T. Waerner, et al. characterized ILEI as a key player in both epithelial to mesenchymal transition and late-stage carcinoma progression. EMT is a process that involves changes in gene expression, cytoskeleton organization, cell adhesion, and extracellular matrix composition. This process is important during tissue formation and organogenesis, but also during cancer progression, metastasis and chronic inflammation. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FAM3C