ERN2 Antibody

Immunohistochemistry-Paraffin: ERN2 Antibody [NBP3-05980] - Staining of human ERN2 in human liver with rabbit polyclonal antibody at 1:100 dilution.

Immunohistochemistry-Paraffin: ERN2 Antibody [NBP3-05980] - Staining of human ERN2 in human kidney with rabbit polyclonal antibody at 1:100 dilution.

Product Discontinued

ERN2 Antibody Summary

• Description: This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with E. coli-derived Human ERN2 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ERN2
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:200

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH7.0
• Preservative: 0.03% Proclin 300
• Purity: Antigen and protein A Affinity-purified

Alternate Names for ERN2 Antibody

• EC 2.7.11
• endoplasmic reticulum to nucleus signaling 2
• endoplasmic reticulum to nucleus signalling 2
• Endoplasmic reticulum-to-nucleus signaling 2
• ER to nucleus signalling 2
• hIRE2p
• inositol-requiring 1 beta
• Inositol-requiring protein 2
• IRE1, S. cerevisiae, homolog of
• Ire1-beta
• IRE1bIRE1 beta
• IRE2
• serine/threonine-protein kinase/endoribonuclease IRE2

Background

Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ERN2