EMR3 Antibody

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Immunohistochemistry-Paraffin: EMR3 Antibody [NBP1-02665] - Staining of human macrophage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ...read more

Product Details

Summary
Reactivity Hu, Mk, PmSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

EMR3 Antibody Summary

Immunogen
Synthetic 18 amino acid peptide from C-terminal cytoplasmic domain of human EMR3.
Specificity
Human EMR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EMR3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin 5 - 25 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Orangutan (94%), Gibbon (94%), Elephant (89%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for EMR3 Antibody

  • egf-like module containing, mucin-like, hormone receptor-like 3
  • EGF-like module receptor 3
  • EGF-like module-containing mucin-like hormone receptor-like 3
  • egf-like module-containing mucin-like receptor 3
  • EMR3

Background

EMR3 is an Orphan-B GPCR with an unknown ligand. Two variants are produced by alternative splicing. One form encodes a 652-amino acid GPCR consisting of two EGF-like domains and a mucin stalk, while the other is a truncated soluble form containing only two EGF-like domains. EMR3 and EMR2 share a high degree of sequence identity in the transmembrane domains.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol EMR3
Entrez
Uniprot