EMR2 Antibody - BSA Free

Immunohistochemistry-Paraffin: EMR2 Antibody [NLS1663] - Analysis of anti-EMR2 antibody with human spleen.

Immunohistochemistry: EMR2 Antibody [NLS1663] - Analysis of anti-EMR2 antibody with transfection positive.

Immunohistochemistry-Paraffin: EMR2 Antibody [NLS1663] - Analysis of anti-EMR2 antibody with transfected cells expressing EMR2 at 2 ug/ ml.

Immunohistochemistry-Paraffin: EMR2 Antibody [NLS1663] - Analysis of anti-EMR2 antibody with cells expressing vector only using this antibody at 2 ug/ ml.

Immunohistochemistry-Paraffin: EMR2 Antibody [NLS1663] - Analysis of anti-EMR2 antibody with transfection control.

• Reactivity: Hu, Pm
• Applications: ELISA, IHC, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

EMR2 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 20 amino acid peptide from N-terminal extracellular domain of human EMR2.
• Epitope: N-Terminus extracellular domain
• Specificity: Human EMR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MYO18B (45%), FLJ13231 (40%).
• Predicted Species: Primate (90%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ADGRE2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunocytochemistry 1:10 - 1:500
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 7.5 - 15 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (90%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for EMR2 Antibody - BSA Free

• CD312
• DKFZp781B135
• egf-like module containing, mucin-like, hormone receptor-like 2
• egf-like module containing, mucin-like, hormone receptor-like sequence 2
• EGF-like module receptor 2
• EGF-like module-containing mucin-like hormone receptor-like 2
• EMR2

Background

EMR2 is an Orphan-B GPCR with an unknown ligand. EMR2 has five EGF-like domains in the extracellular domain and is highly homologous to CD97. Multiple isoforms of EMR2 are produced by alternative splicing. EMR2 has been reported to be expressed in immune tissues, where it has been shown to be restricted specifically to monocytes and granulocytes. ESTs have been isolated from blood, colon, lymph node, placenta, spleen, testis, and uterus libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ADGRE2
• Entrez:
  • 30817(Human)