Human Cysteine Conjugate beta-Lyase/CCBL1 ELISA Kit (Colorimetric)

ELISA: Human Cysteine Conjugate beta-Lyase/CCBL1 ELISA Kit (Colorimetric) [NBP3-27300] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Tissue homogenates, cell lysates and other biological fluids
• Standard Curve Range: 78.125 - 5000 pg/mL (example only; lot dependent)
• Sensitivity: 27 pg/mL (example only; lot dependent)

Human Cysteine Conjugate beta-Lyase/CCBL1 ELISA Kit (Colorimetric) Summary

• Description: Assay Length: 4.5 hours
• Standard Curve Range: 78.125 - 5000 pg/mL (example only; lot dependent)
• Sensitivity: 27 pg/mL (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Inter-Assay: %CV < 12 (example only; lot dependent)
• Intra-Assay: %CV < 10 (example only; lot dependent)
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: KYAT1

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Cysteine Conjugate beta-Lyase/CCBL1 ELISA Kit (Colorimetric)

• CCBL1
• Cysteine Conjugate betaLyase
• Cysteine Conjugate beta-Lyase
• cysteine conjugate-beta lyase, cytoplasmic
• cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K
• Cysteine-S-conjugate beta-lyase
• EC 2.6.1.64
• EC 2.6.1.7
• EC 4.4.1.13
• FLJ95217
• Glutamine Transaminase K
• glutamine-phenylpyruvate aminotransferase
• Glutamine--phenylpyruvate transaminase
• GTKMGC29624
• KAT1
• KATI
• KATIbeta-lysase, kidney
• Kyneurenine Aminotransferase I
• kyneurenine aminotransferase
• kyneurenine aminotransferase)
• Kynurenine aminotransferase I
• kynurenine--oxoglutarate transaminase 1
• Kynurenine--oxoglutarate transaminase I

Background

CCBL1 encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: KYAT1