Cysteine Conjugate beta-Lyase/CCBL1 Antibody

Western Blot: Cysteine Conjugate beta-Lyase/CCBL1 Antibody [H00000883-B02P] - Analysis of CCBL1 expression in transfected 293T cell line by CCBL1 polyclonal antibody. Lane1:CCBL1 transfected lysate(27.5 KDa). Lane2:Non-transfected lysate.

Product Discontinued

Cysteine Conjugate beta-Lyase/CCBL1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: CCBL1 (AAH21262.1, 1 a.a. - 250 a.a.) full-length human protein. MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIVSAAVLFGLGQPASLACGNGP
• Specificity: CCBL1 - cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: KYAT1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cysteine Conjugate beta-Lyase/CCBL1 Antibody

• CCBL1
• Cysteine Conjugate betaLyase
• Cysteine Conjugate beta-Lyase
• cysteine conjugate-beta lyase, cytoplasmic
• cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K
• Cysteine-S-conjugate beta-lyase
• EC 2.6.1.64
• EC 2.6.1.7
• EC 4.4.1.13
• FLJ95217
• Glutamine Transaminase K
• glutamine-phenylpyruvate aminotransferase
• Glutamine--phenylpyruvate transaminase
• GTKMGC29624
• KAT1
• KATI
• KATIbeta-lysase, kidney
• Kyneurenine Aminotransferase I
• kyneurenine aminotransferase
• kyneurenine aminotransferase)
• Kynurenine aminotransferase I
• kynurenine--oxoglutarate transaminase 1
• Kynurenine--oxoglutarate transaminase I

Background

This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KYAT1
• Entrez:
  • 883(Human)
• Uniprot:
  • AAH21262.1(Human)