CUEDC1 Antibody - BSA Free

Western Blot: CUEDC1 Antibody [NBP1-76946] - Rat liver tissue lysate with CUEDC1 antibody at (A) 0.5 and (B) 1 ug/ml.

Immunocytochemistry/ Immunofluorescence: CUEDC1 Antibody - BSA Free [NBP1-76946] - Immunofluorescence of CUEDC1 in human liver tissue with CUEDC1 antibody at 20 ug/mL.

Immunohistochemistry: CUEDC1 Antibody - BSA Free [NBP1-76946] - Immunohistochemistry of CUEDC1 in human liver tissue with CUEDC1 antibody at 2 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CUEDC1 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human CUEDC1. The immunogen is located within amino acids 310 - 360 of CUEDC1. Amino Acid Squence: AFSEKTKMRKSKRKHL
• Specificity: CUEDC1 antibody will not cross-react with CUEDC2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CUEDC1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2 ug/ml
  • Immunohistochemistry-Paraffin 2 ug/ml
  • Western Blot 0.5-1 ug/ml
• Control Peptide:

  CUEDC1 Peptide (NBP1-76946PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for CUEDC1 Antibody - BSA Free

• CUE domain containing 1
• CUE domain-containing protein 1
• DKFZp547L163
• FLJ20739

Background

The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events. Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker. CUEDC1 antibody will not cross-react with CUEDC2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CUEDC1
• Uniprot:
  • AAH56882(Human)