Connexin 62/GJA10 Antibody

Immunohistochemistry-Paraffin: Connexin 62/GJA10 Antibody [NBP2-14050] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.

Product Discontinued

Connexin 62/GJA10 Antibody Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to the amino acids: SEGIEDETGPPFHLKKYSVAQQCMICSSLPERISPLQANNQQQVIRVNVPKSKTMWQIPQPRQLEVDPSNGKKDWSEKDQHSGQLHVHSPCPWAGSAGNQHLGQQSDHSSFGLQNTMSQSWLGT
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GJA10
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Connexin 62/GJA10 Antibody

• Connexin 62
• connexin-62
• Cx62
• CX62gap junction alpha-10 protein
• gap junction protein, alpha 10, 62kDa
• GJA10
• RP11-63K6.6

Background

Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GJA10