Cofilin Antibody (1093310) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB, IHC, ICC/IF
• Clone: 1093310
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Cofilin Antibody (1093310) [Alexa Fluor® 488] Summary

• Immunogen: Synthetic Peptide
  Accession # P23528
• Specificity: Detects a synthetic peptide specific for human CFL1 around aa 30 in Direct ELISA.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Cofilin Antibody (1093310) [Alexa Fluor® 488]

• 18 kDa phosphoprotein
• CFL
• CFL1
• cofilin 1 (non-muscle)
• cofilin
• Cofilin, non-muscle isoform
• cofilin-1
• HEL-S-15
• p18

Background

Cofilin-1 (CFL1) is an 18.5 kDa protein that is a member of the actin deploy family (ADF). It is involved in the biological activities of various malignancies, including infiltration, metastasis, and chemotherapy resistance. Overexpression of CFL is associated with aggressive features and poor prognosis in malignancies. CFL1 also plays a crucial role in B cell, T cell infiltration, cytokine and NF-kappa B signaling pathways and can serve as a useful biomarker for diagnosis of inflammatory diseases.  

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.