CDC37L1 Antibody

Product Discontinued

CDC37L1 Antibody Summary

• Immunogen: Synthetic peptide: HKEDDEPKMMDTV, representing the to C- terminus of the human protein (residues 325-337), according to NP_060383.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CDC37L1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA 1:32000
• Application Notes: Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Preliminary experiments gave an approx 20kDa band in human liver lysates at 0.5ug/ml. This band was successfully blocked by incubation with the immunising peptide. Please note that currently we cannot find an explanation in the literature for the band we observe given the predicted size of approx. 39kDda according to NP_060383. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
• Control:

  CDC37L1 Overexpression Lysate

Reactivity Notes

Cross reacts with Human. Expected from sequence similarity: Mouse, Rat and Dog.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for CDC37L1 Antibody

• CDC37 cell division cycle 37 homolog (S. cerevisiae)-like 1
• CDC37BHARCCDC37 cell division cycle 37 homolog-like 1
• cell division cycle 37 homolog (S. cerevisiae)-like 1
• FLJ20639
• hsp90 co-chaperone Cdc37-like 1
• Hsp90-associating relative of Cdc37

Background

CDC37L1 is a cytoplasmic phosphoprotein that exists in complex with HSP90 (HSPCA; MIM 140571) as well as several other proteins involved in HSP90-mediated protein folding (Scholz et al., 2001 (PubMed 11413142)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDC37L1
• Entrez:
  • 55664(Human)
• Uniprot:
  • NP_060383.(Human)