CCT8 Antibody

Western Blot: CCT8 Antibody [H00010694-B02P] - Analysis of CCT8 expression in human spleen.

Western Blot: CCT8 Antibody [H00010694-B02P] - Analysis of CCT8 expression in Jurkat.

Western Blot: CCT8 Antibody [H00010694-B02P] - Analysis of CCT8 expression in transfected 293T cell line by CCT8 polyclonal antibody. Lane 1: CCT8 transfected lysate(60.28 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

CCT8 Antibody Summary

• Immunogen: CCT8 (NP_006576.2, 1 a.a. - 548 a.a.) full-length human protein. MALHVPKAPGFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSGISSSSVLHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKDWDDDQND
• Specificity: Reacts with chaperonin containing TCP1, subunit 8 (theta).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: CCT8
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is reactive against tissue and transfected lysate in western blot, and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CCT8 Antibody

• C21orf112
• Cctq
• CCT-theta
• chaperonin containing TCP1, subunit 8 (theta)
• chromosome 21 open reading frame 112
• D21S246
• KIAA0002
• PRED71
• T-complex protein 1 subunit theta
• T-complex protein 1, theta subunit, 10Renal carcinoma antigen NY-REN-15
• TCP-1-theta

Background

Molecular chaperone; assist the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CCT8 Antibody (H00010694-B02P)(2)

Publications using H00010694-B02P

• Knowlton JJ, Fernandez de Castro I, Ashbrook AW et al. The TRiC chaperonin controls reovirus replication through outer-capsid folding. Nat Microbiol. 2018-04-01 [PMID: 29531365] (Human)
• Neef DW, Turski ML, Thiele DJ. Modulation of heat shock transcription factor 1 as a therapeutic target for small molecule intervention in neurodegenerative disease. PLoS Biol 8(1):e1000291. 2010-01-19 [PMID: 20098725]

Bioinformatics

• Gene Symbol: CCT8
• Entrez:
  • 10694(Human)
• Uniprot:
  • NP_006576.2(Human)