CAPS2 Antibody - BSA Free

Western Blot: CAPS2 Antibody [NBP1-76898] - Human brain tissue lysate with CAPS2 antibody at (A) 0.5 and (B) 1 ug/ml.

Immunocytochemistry/Immunofluorescence: CAPS2 Antibody [NBP1-76898] - Immunofluorescence of CAPS2 in Human Brain cells with CAPS2 antibody at 20 ug/mL.

Immunohistochemistry-Paraffin: CAPS2 Antibody [NBP1-76898] - Human brain with CAPS2 antibody at 5 ug/ml.

Product Discontinued

CAPS2 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 19 amino acid synthetic peptide near the center of the human CAPS2. The immunogen is located within amino acids 510 - 560 of CAPS2. Amino Acid Squence: CSYREKKSEPQELMQLEGY
• Specificity: Multiple isoforms of CAPS2 are known to exist. This CAPS2 antibody is predicted to be specific to CAPS2 and not recognize CAPS1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CAPS2
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 0.5-1 ug/ml
• Theoretical MW: 150 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for CAPS2 Antibody - BSA Free

• calcyphosin-2
• calcyphosine 2
• calcyphosine-2
• calcyphosphine 2
• FLJ34520

Background

CAPS2 and the related protein CAPS1 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. Like CAPS1, numerous isoforms of CAPS2 are known to exist. These isoforms show distinct expression patterns in the brain. For example, CAPS2b showed high expression in the developing cerebellum. Furthermore, one version of CAPS2 mRNA that lacks exon 3 is detected in some autistic patients, suggesting that the differential expression pattern of CAPS2 is involved in neuronal development. This CAPS2 antibody is predicted to be specific to CAPS2 and not recognize CAPS1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CAPS2
• Uniprot:
  • NP_060424(Human)