Calpain 7 Antibody [Janelia Fluor® 525]

Product Discontinued

Calpain 7 Antibody [Janelia Fluor® 525] Summary

• Immunogen: calpain 7. (Uniprot# Q9Y6W3)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CAPN7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Calpain 7 Antibody [Janelia Fluor® 525]

• calpain 7
• calpain like protease
• CALPAIN7
• EC 3.4.22
• EC 3.4.22.-
• FLJ36423
• homolog of Aspergillus Nidulans PALB
• PalB homolog
• PalBH
• PALBHcalpain-7

Background

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CAPN7