AP2A2 Antibody


Western Blot: AP2A2 Antibody [NBP1-68948] - Human Lung lysate, concentration 0.2-1 ug/ml.

Product Details

Reactivity HuSpecies Glossary
Applications WB
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

AP2A2 Antibody Summary

Synthetic peptides corresponding to AP2A2 (adaptor-related protein complex 2, alpha 2 subunit) The peptide sequence was selected from the C terminal of AP2A2 (NP_036437). Peptide sequence LAKLKKKKGPSTVTDLEDTKRDRSVDVNGGPEPAPASTSAVSTPSPSADL.
This product is specific to Subunit or Isofrom: alpha-2.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
From PBS.
No Preservative
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified


Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
104 kDa


The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for AP2A2 Antibody

  • 100 kDa coated vesicle protein C
  • Adapter-related protein complex 2 alpha-2 subunit
  • adaptin, alpha B
  • Adaptor protein complex AP-2 subunit alpha-2
  • adaptor-related protein complex 2, alpha 2 subunit
  • alpha2-adaptin
  • Alpha-adaptin C
  • alpha-adaptin C; Huntingtin interacting protein J
  • AP-2 complex subunit alpha-2
  • Clathrin assembly protein complex 2 alpha-C large chain
  • clathrin-associated/assembly/adaptor protein, large, alpha 2
  • DKFZP564D1864
  • Huntingtin yeast partner J
  • Huntingtin-interacting protein 9
  • Huntingtin-interacting protein J
  • KIAA0899HIP-9
  • Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit


AP2A2 is a component of the adaptor protein complex 2 (AP-2). AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

Additional AP2A2 Antibody Products

AP2A2 NBP1-68948

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Contact Information

Product PDFs


Gene Symbol AP2A2

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