AIPL1 Antibody Blocking Peptide Summary
| Description |
A blocking peptide containing 18 amino acids near the center of human Aipl1. Source: Synthetic (Accession #: NP_055151) |
| Source |
Synthetic |
| Protein/Peptide Type |
Antibody Blocking Peptide |
| Gene |
AIPL1 |
| Purity |
N/A |
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This peptide is useful as a blocking peptide for NBP1-76956. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles. |
| Buffer |
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin. |
| Preservative |
0.02% Sodium Azide |
| Concentration |
0.2 mg/ml |
| Purity |
N/A |
Alternate Names for AIPL1 Antibody Blocking Peptide
Background
Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are diagnosed at birth or in the first few months of life with severely impaired vision or blindness, nystagmus and an abnormal or flat electroretinogram. The photoreceptor/pineal -expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, was mapped within the LCA4 candidate region. The protein contains three tetratricopeptide motifs, consistent with nuclear transport or chaperone activity. AIPL1 mutations may cause approximately 20% of recessive LCA. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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