IL-5 Products

Description

IL-5 (T cell replacing factor (TRF), eosinophil differentiation factor (EDF)) is a hematopoietic growth factor that stimulates the proliferation, differentiation and activation of eosinophils. It is produced by mast cells, T cells and eosinophils and has an important role in activating cell-mediated immunity following parasitic infections. It belongs to the same cytokine family as IL-3 and GM-CSF. The biologically active IL-5 consists of an antiparallel homodimer linked by disulfide bonds. Human and murine IL-5 are 70% identical at the amino acid level and show species cross-reactivity. IL-5 exerts its effects on target cells by binding to specific cell surface receptors.

Bioinformatics

Entrez	16191 Mouse 24497 Rat 3567 Human
Uniprot	NP_000870 Human NP_000870.1 Human P04401 Mouse P05113 Human
Product By Gene ID	3567
Alternate Names	B-cell differentiation factor I EDF Eosinophil differentiation factor IL-5T-cell replacing factor interleukin 5 (colony-stimulating factor, eosinophil) interleukin-5 TRFB cell differentiation factor I

Research Areas for IL-5

Find related products by research area and learn more about each of the different research areas below.

Asthma
Biologically Active Proteins
Cell Cycle and Replication
Cytokine Research
Immunology