| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NBP1-87781-25ul | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NBP3-35912-20ul | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Azide and BSA Free | NBP3-43977 | |||
| BSA Free | NBP3-07989-25ul | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Azide and BSA Free | NBP3-08534 | |||
![Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining in human cerebral cortex and pancreas tissues using anti-PLP1 antibody. Corresponding PLP1 RNA-seq data are presented for the same tissues.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-Immunohistochemistry-Paraffin-NBP1-87781-img0012.jpg "<b>Orthogonal Strategies Validation. </b>Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining in human cerebral cortex and pancreas tissues using anti-PLP1 antibody. Corresponding PLP1 RNA-seq data are presented for the same tissues.")
![<b>Orthogonal Strategies Validation. </b>Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Border of a demyelinated lesion. Image submitted by a verified customer review.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-Immunohistochemistry-Paraffin-NBP1-87781-img0013.jpg)
![Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining of human cerebral cortex shows high expression.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-Immunohistochemistry-Paraffin-NBP1-87781-img0010.jpg)
![Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-87781] - Staining of human pancreas shows low expression as expected.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-Immunohistochemistry-Paraffin-NBP1-87781-img0011.jpg)
![Western Blot: Myelin PLP Antibody [NB100-74503] - Proteins were extracted from control (Ctrl) and stretched (Stretch) 158N cells and western blot was performed for myelin protein PLP (26 kDa) following 20% of strain. Beta-Actin was used as a loading control. Results represent the mean +/- SEM of three independent experiments. Image collected and cropped by CiteAb from the following publication (//www.ncbi.nlm.nih.gov/pmc/articles/PMC6505516/) licensed under a CC-BY license.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-Western-Blot-NB100-74503-img0003.jpg "Western Blot: Myelin PLP Antibody [NB100-74503] - Proteins were extracted from control (Ctrl) and stretched (Stretch) 158N cells and western blot was performed for myelin protein PLP (26 kDa) following 20% of strain. Beta-Actin was used as a loading control. Results represent the mean +/- SEM of three independent experiments. Image collected and cropped by CiteAb from the following publication (//www.ncbi.nlm.nih.gov/pmc/articles/PMC6505516/) licensed under a CC-BY license.")
![Western Blot: Myelin PLP Antibody [NB100-74503] - Figure 1 shows a Western blot of PLP in adult mouse brain samples using NB100-74503. Figure 2 shows an immunocytochemical staining of PLP in mouse brain thick section using NB100-74503. Staining (m) is limited to myelin tracts and oligodendrocytes.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-Western-Blot-NB100-74503-img0001.jpg)
![Western Blot: Myelin PLP Antibody [NB100-74503] - Analysis of adult mouse brain samples.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-Western-Blot-NB100-74503-img0002.jpg)
![Western Blot: Myelin PLP Antibody [NB100-74503] - Alteration in myelin gene expression after in vitro mechanical tensile strain of 20% & 30%. Total RNA was extracted & RT-qPCR was performed in control (Ctrl) & stretched (Stretch) cells for myelin genes Mag (a, d), Cnp (b, e), & Plp (c, f, g, i) after strain of 20% (a, b, c, g) & 30% (d, e, f, i). Results represent the mean ± SEM of three independent experiments performed in triplicate. *p < 0.05; **p < 0.01. (h, j) Proteins were extracted from control (Ctrl) & stretched (Stretch) 158N cells & western blot was performed for myelin protein PLP (26 kDa) following 20% (h) & 30% (j) of strain. beta -Actin was used as a loading control. Results represent the mean ± SEM of three independent experiments Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30298339), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb100-74503_rabbit-polyclonal-myelin-plp-antibody-310202415392571.jpg)
![Western Blot: Myelin PLP Antibody [NB100-74503] - Alteration in myelin gene expression after in vitro mechanical tensile strain of 20% & 30%. Total RNA was extracted & RT-qPCR was performed in control (Ctrl) & stretched (Stretch) cells for myelin genes Mag (a, d), Cnp (b, e), & Plp (c, f, g, i) after strain of 20% (a, b, c, g) & 30% (d, e, f, i). Results represent the mean ± SEM of three independent experiments performed in triplicate. *p < 0.05; **p < 0.01. (h, j) Proteins were extracted from control (Ctrl) & stretched (Stretch) 158N cells & western blot was performed for myelin protein PLP (26 kDa) following 20% (h) & 30% (j) of strain. beta -Actin was used as a loading control. Results represent the mean ± SEM of three independent experiments Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30298339), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb100-74503_rabbit-polyclonal-myelin-plp-antibody-310202415334915.jpg)
![Western Blot: Myelin PLP Antibody [NB100-74503] - Mechanical tensile strain of 30% induces an elongation of paranodal junction & alteration in MAPK signaling in organotypic cerebellar slice culture. a Double immunostaining of organotypic cerebellar slices for CASPR in red & MAG in green. The response was evaluated at time 0 h post-stretch. Altered paranodal junctions are highlighted within white circles in high-magnification images. Scale bar, 50 μm; inset scale bar, 5 μm. b Sketch of CASPR & MAG labeling in the paranodal junction. Quantitative analysis is characterized by three length measurements: c nodal length called (A); d paranodal length called (B); & e (B-A) corresponding to the total length of the CASPR labeling. f–h Proteins were extracted following strain of 30% from control (Ctrl) & stretched (Stretch) slices & western blot was performed for the myelin protein MBP (f), ERK1/2 (g), & p38 (h). The ratio P-ERK on total ERK & the ratio P-p38 on total p38 are presented. beta -Actin was used as a loading control. Results represent the mean ± SEM (n = 3). ***p < 0.001. CASPR contactin-associated protein, MAG myelin-associated glycoprotein Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30298339), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb100-74503_rabbit-polyclonal-myelin-plp-antibody-3102024168216.jpg)
![Western Blot: Myelin PLP Antibody [NB100-74503] - Mechanical tensile strain of 30% induces an elongation of paranodal junction & alteration in MAPK signaling in organotypic cerebellar slice culture. a Double immunostaining of organotypic cerebellar slices for CASPR in red & MAG in green. The response was evaluated at time 0 h post-stretch. Altered paranodal junctions are highlighted within white circles in high-magnification images. Scale bar, 50 μm; inset scale bar, 5 μm. b Sketch of CASPR & MAG labeling in the paranodal junction. Quantitative analysis is characterized by three length measurements: c nodal length called (A); d paranodal length called (B); & e (B-A) corresponding to the total length of the CASPR labeling. f–h Proteins were extracted following strain of 30% from control (Ctrl) & stretched (Stretch) slices & western blot was performed for the myelin protein MBP (f), ERK1/2 (g), & p38 (h). The ratio P-ERK on total ERK & the ratio P-p38 on total p38 are presented. beta -Actin was used as a loading control. Results represent the mean ± SEM (n = 3). ***p < 0.001. CASPR contactin-associated protein, MAG myelin-associated glycoprotein Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30298339), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb100-74503_rabbit-polyclonal-myelin-plp-antibody-31020241555233.jpg)
![Western Blot: Myelin PLP Antibody [NB100-74503] - Mechanical tensile strain of 30% induces an elongation of paranodal junction & alteration in MAPK signaling in organotypic cerebellar slice culture. a Double immunostaining of organotypic cerebellar slices for CASPR in red & MAG in green. The response was evaluated at time 0 h post-stretch. Altered paranodal junctions are highlighted within white circles in high-magnification images. Scale bar, 50 μm; inset scale bar, 5 μm. b Sketch of CASPR & MAG labeling in the paranodal junction. Quantitative analysis is characterized by three length measurements: c nodal length called (A); d paranodal length called (B); & e (B-A) corresponding to the total length of the CASPR labeling. f–h Proteins were extracted following strain of 30% from control (Ctrl) & stretched (Stretch) slices & western blot was performed for the myelin protein MBP (f), ERK1/2 (g), & p38 (h). The ratio P-ERK on total ERK & the ratio P-p38 on total p38 are presented. beta -Actin was used as a loading control. Results represent the mean ± SEM (n = 3). ***p < 0.001. CASPR contactin-associated protein, MAG myelin-associated glycoprotein Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30298339), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb100-74503_rabbit-polyclonal-myelin-plp-antibody-3102024165743.jpg)
![Immunocytochemistry/Immunofluorescence: Myelin PLP Antibody [NB100-1608] - Immunohistochemistry photomicrograph of PLP immunoreactivity (Green; 1:1000 dilution) in a cryostat section of an embryonic (e18) mouse brain. blue is DAPI nuclear counterstain.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-Immunocytochemistry-Immunofluorescence-NB100-1608-img0001.jpg "Immunocytochemistry/Immunofluorescence: Myelin PLP Antibody [NB100-1608] - Immunohistochemistry photomicrograph of PLP immunoreactivity (Green; 1:1000 dilution) in a cryostat section of an embryonic (e18) mouse brain. blue is DAPI nuclear counterstain.")
![Western Blot: Myelin PLP Antibody [NBP3-35912] - Western blot analysis of various lysates, using Myelin PLP Rabbit pAb at 1:2000 dilution.Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.](http://images.novusbio.com/fullsize/nbp3-35912_rabbit-myelin-plp-pab-9122024141812.jpg "Western Blot: Myelin PLP Antibody [NBP3-35912] - Western blot analysis of various lysates, using Myelin PLP Rabbit pAb at 1:2000 dilution.Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 30s.")
![Immunohistochemistry: Myelin PLP Antibody [NBP3-35912] - Immunohistochemistry analysis of paraffin-embedded Mouse brain using Myelin PLP Rabbit pAb at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.](http://images.novusbio.com/fullsize/nbp3-35912_rabbit-myelin-plp-pab-912202415121368.jpg)
![Immunocytochemistry/ Immunofluorescence: Myelin PLP Antibody [NBP3-35912] - Immunofluorescence analysis of paraffin-embedded mouse brain using Myelin PLP Rabbit pAb at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](http://images.novusbio.com/fullsize/nbp3-35912_rabbit-myelin-plp-pab-912202414201388.jpg)
![Immunocytochemistry/ Immunofluorescence: Myelin PLP Antibody [NBP3-35912] - Immunofluorescence analysis of paraffin-embedded rat brain using Myelin PLP Rabbit pAb at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](http://images.novusbio.com/fullsize/nbp3-35912_rabbit-myelin-plp-pab-912202415175210.jpg)
![Immunohistochemistry: Myelin PLP Antibody [NBP3-35912] - Immunohistochemistry analysis of paraffin-embedded Rat brain using Myelin PLP Rabbit pAb at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.](http://images.novusbio.com/fullsize/nbp3-35912_rabbit-myelin-plp-pab-912202414154342.jpg)
![Immunohistochemistry-Paraffin: Myelin PLP Antibody (CL10622) [NBP3-07989] - Analysis in human cerebral cortex and tonsil tissues using NBP3-07989 antibody. Corresponding Myelin PLP RNA-seq data are presented for the same tissues.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-CL10622-Immunohistochemistry-Paraffin-NBP3-07989-img0001.jpg "<b>Orthogonal Strategies Validation. </b>Immunohistochemistry-Paraffin: Myelin PLP Antibody (CL10622) [NBP3-07989] - Analysis in human cerebral cortex and tonsil tissues using NBP3-07989 antibody. Corresponding Myelin PLP RNA-seq data are presented for the same tissues.")
![<b>Orthogonal Strategies Validation. </b>Immunohistochemistry-Paraffin: Myelin PLP Antibody (CL10622) [NBP3-07989] - Staining of human tonsil shows no positivity in lymphoid cells as expected.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-CL10622-Immunohistochemistry-Paraffin-NBP3-07989-img0005.jpg)
![Immunohistochemistry-Paraffin: Myelin PLP Antibody (CL10622) [NBP3-07989] - Staining of human cerebellum shows strong positivity in myelinated neuronal processes.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-CL10622-Immunohistochemistry-Paraffin-NBP3-07989-img0002.jpg)
![Immunohistochemistry-Paraffin: Myelin PLP Antibody (CL10622) [NBP3-07989] - Staining of human cerebral cortex shows strong positivity in myelinated neural fibers.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-CL10622-Immunohistochemistry-Paraffin-NBP3-07989-img0003.jpg)
![Immunohistochemistry-Paraffin: Myelin PLP Antibody (CL10622) [NBP3-07989] - Staining of human kidney shows no positivity as expected.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-CL10622-Immunohistochemistry-Paraffin-NBP3-07989-img0004.jpg)
![Immunohistochemistry-Paraffin: Myelin PLP Antibody (CL10622) [NBP3-07989] - Staining of rat cerebral cortex shows strong positivity in myelinated neuronal processes and in oligodendrocytes cell bodies.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-CL10622-Immunohistochemistry-Paraffin-NBP3-07989-img0006.jpg)
![Immunohistochemistry-Paraffin: Myelin PLP Antibody (PLP1/4259) [NBP3-07603] - Formalin-fixed, paraffin-embedded human brain stained with Myelin PLP Mouse Monoclonal Antibody (PLP1/4259).](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-PLP1-4259-Immunohistochemistry-Paraffin-NBP3-07603-img0001.jpg "Immunohistochemistry-Paraffin: Myelin PLP Antibody (PLP1/4259) [NBP3-07603] - Formalin-fixed, paraffin-embedded human brain stained with Myelin PLP Mouse Monoclonal Antibody (PLP1/4259).")
![Flow Cytometry: Myelin PLP Antibody (PLP1/4259) [NBP3-07603] - Total extracellular vesicles with Myelin PLP Antibody (PLP1/4259) [Alexa Fluor® 647] (Catalog # NBP3-08534AF647) (left). Gate determined vesicles positive for PLP1 antibody ranging from 500-800nm size. Image on the right represents the same sample without antibody. 10ul of pre-isolated extracellular vesicles were incubated with 2ul of Myelin PLP Antibody (PLP1/4259) [Alexa Fluor® 647] , during 20 minutes at room temperature, and analyzed in nanoscale flow cytometer able to resolve particles scattering as little as 100um. Image from a verified customer review.](http://images.novusbio.com/fullsize/nbp3-07603_mouse-monoclonal-myelin-plp-antibody-plp1-4259-71020241132520.png)
![Western Blot: Myelin PLP Antibody [NBP1-60071] - 721_B cell lysate, Antibody Titration: 0.2-1 ug/ml.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-Western-Blot-NBP1-60071-img0002.jpg "Western Blot: Myelin PLP Antibody [NBP1-60071] - 721_B cell lysate, Antibody Titration: 0.2-1 ug/ml.")
![Immunohistochemistry-Paraffin: Myelin PLP Antibody [NBP1-60071] - Human Brain, cerebellum tissue at an antibody concentration of 5ug/ml.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-Immunohistochemistry-Paraffin-NBP1-60071-img0003.jpg)
![SDS-Page: Recombinant Human Myelin PLP Protein [H00005354-Q01] - 12.5% SDS-PAGE Stained with Coomassie Blue.](http://images.novusbio.com/fullsize/qc_test-H00005354-Q01-1.jpg "SDS-Page: Recombinant Human Myelin PLP Protein [H00005354-Q01] - 12.5% SDS-PAGE Stained with Coomassie Blue.")
![Immunocytochemistry/Immunofluorescence: Myelin PLP Antibody (2D7) [H00005354-M03] - Analysis of monoclonal antibody to PLP1 on HeLa cell. Antibody concentration 10 ug/ml](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-2D7-Immunocytochemistry-Immunofluorescence-H00005354-M03-img0004.jpg "Immunocytochemistry/Immunofluorescence: Myelin PLP Antibody (2D7) [H00005354-M03] - Analysis of monoclonal antibody to PLP1 on HeLa cell. Antibody concentration 10 ug/ml")
![ELISA: Myelin PLP Antibody (2D7) [H00005354-M03] - Detection limit for recombinant GST tagged PLP1 is approximately 0.1ng/ml as a capture antibody.](http://images.novusbio.com/fullsize/Myelin-PLP-Antibody-2D7-ELISA-H00005354-M03-img0003.jpg)
![ELISA: Human Myelin PLP ELISA Kit (Colorimetric) [NBP3-00412] - Samples were spiked with high concentrations of Human Myelin PLP and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.](http://images.novusbio.com/fullsize/nbp3-00412_human-myelin-plp-elisa-kit-colorimetric-132202416133643.jpg "ELISA: Human Myelin PLP ELISA Kit (Colorimetric) [NBP3-00412] - Samples were spiked with high concentrations of Human Myelin PLP and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.")
![ELISA: Human Myelin PLP ELISA Kit (Colorimetric) [NBP3-00412] - Standard Curve Reference](http://images.novusbio.com/fullsize/nbp3-00412_human-myelin-plp-elisa-kit-colorimetric-4320249133240.jpg)
![Western Blot: Myelin PLP Overexpression Lysate (Adult Normal) [NBL1-14523] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Myelin PLP.](http://images.novusbio.com/fullsize/Myelin-PLP-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-14523-img0002.jpg "Western Blot: Myelin PLP Overexpression Lysate (Adult Normal) [NBL1-14523] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Myelin PLP.")