RIPK3/RIP3 Products

Antibodies
RIPK3/RIP3 Antibody
RIPK3/RIP3 Antibody
NBP1-77299
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IF
Host: Rabbit Polyclonal
RIPK3/RIP3 Antibody
RIPK3/RIP3 Antibody
NBP2-24588
Species: Hu, Pm, Mu(-)
Applications: WB, ICC/IF, IHC-P
Host: Rabbit Polyclonal
RIPK3/RIP3 Antibody (780115) ...
RIPK3/RIP3 Antibody (780115) [Unco...
MAB7604
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Lysates
RIPK3/RIP3 Overexpression Lys ...
RIPK3/RIP3 Overexpression Lysate (...
NBL1-15379
Applications: WB
Proteins
RIPK3/RIP3 Recombinant Protei ...
RIPK3/RIP3 Recombinant Protein
H00011035-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE, KA
RIPK3/RIP3 Partial Recombinan ...
RIPK3/RIP3 Partial Recombinant Pro...
H00011035-Q01
Species: Hu
Applications: WB, ELISA, PA
RIPK3/RIP3 Recombinant Protei ...
RIPK3/RIP3 Recombinant Protein Ant...
NBP2-49167PEP
Species: Hu
Applications: AC
RNAi
RIPK3/RIP3 RNAi
RIPK3/RIP3 RNAi
H00011035-R04
Species: Hu

Description

Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3 (1-3). RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-kappaB activation. Overexpression of RIP3 induces apoptosis and NF-kappaB activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues (2,3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Mouse
Mouse
Product By Gene ID 11035
Alternate Names
  • EC 2.7.11.1
  • RIP-3
  • receptor-interacting serine/threonine-protein kinase 3
  • Receptor-interacting protein 3
  • RIP3receptor interacting protein 3
  • RIP-like protein kinase 3
  • receptor-interacting serine-threonine kinase 3

Research Areas for RIPK3/RIP3

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

PTMs for RIPK3/RIP3

Learn more about PTMs related to RIPK3/RIP3.

Phosphorylation
Cleavage
Ubiquitination
Methylation
Demethylation
Nitration

Bioinformatics Tool for RIPK3/RIP3

Discover related pathways, diseases and genes to RIPK3/RIP3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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