Fas Ligand/TNFSF6 Products

Antibodies
Fas Ligand/TNFSF6 Antibody (1 ...
Fas Ligand/TNFSF6 Antibody (100419)
MAB126
Species: Hu
Applications: ELISA(Cap), Neut
Host: Mouse Monoclonal
Fas Ligand/TNFSF6 Antibody (A ...
Fas Ligand/TNFSF6 Antibody (A11)
NBP1-97519
Species: Mu
Applications: Flow, IHC, IHC-Fr, IHC-P
Host: Rat Monoclonal
Fas Ligand/TNFSF6 Antibody
Fas Ligand/TNFSF6 Antibody
AF126
Species: Hu
Applications: WB, IHC, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Antibody Pairs
Fas Ligand/TNFSF6 Antibody Pa ...
Fas Ligand/TNFSF6 Antibody Pair
H00000356-PW1
Species: Hu
Applications: WB, IP
ELISA Kits
Fas Ligand/TNFSF6 ELISA Kit
Fas Ligand/TNFSF6 ELISA Kit
NBP1-91262
Species: Hu
Applications: ELISA
Fas Ligand/TNFSF6 ELISA Kit [ ...
Fas Ligand/TNFSF6 ELISA Kit [Biotin]
KA0159
Species: Hu
Fas Ligand/TNFSF6 ELISA Kit [ ...
Fas Ligand/TNFSF6 ELISA Kit [Biotin]
KA1825
Species: Rt
Lysates
Fas Ligand/TNFSF6 Overexpress ...
Fas Ligand/TNFSF6 Overexpression L...
H00000356-T01
Species: Hu
Applications: WB
Fas Ligand/TNFSF6 Overexpress ...
Fas Ligand/TNFSF6 Overexpression L...
NBL1-10600
Applications: WB
Proteins
Human Fas Ligand/TNFSF6 Prote ...
Human Fas Ligand/TNFSF6 Protein
NBP2-35264
Species: Hu
Applications: Func, PAGE
Fas Ligand/TNFSF6 Recombinant ...
Fas Ligand/TNFSF6 Recombinant Prot...
NBP2-49160PEP
Species: Hu
Applications: AC
Recombinant Human Fas Ligand/ ...
Recombinant Human Fas Ligand/TNFSF...
NBP2-23039
Species: Hu
Applications: PAGE
RNAi
Fas Ligand/TNFSF6 RNAi
Fas Ligand/TNFSF6 RNAi
H00000356-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Fas / APO-1 (CD95) is an important member of the tumour necrosis factor (TNF) superfamily involved in membrane-mediated apoptosis. Ligation of Fas by Fas Ligand (Fas-L) or an anti-Fas cross-linking antibody, triggers activation of the caspase cascade. Functional impairment of the Fas / Fas-L system is associated with the development and progression of malignancies. Fas gene mutations have been suggested to have a role in testicular germ cell tumours. Tumour cells frequently exhibit de novo expression of Fas Ligand (Fas-L), which plays a significant role in local tissue destruction, metastatic spread, and immune escape of the tumor cells. The apoptosis of lymphocytes, which occurs in autoimmune diseases, is usually induced by the Fas/Fas-L system. Fas is believed to be involved in various autoimmune diseases including, ulcerative colitis, Graves disease, and rheumatoid arthritis. Fas expression on gastric epithelial cells in patients infected with H.Pylori is responsible for the accelerated apoptosis of the cells. Serum Fas-L concentration has also been shown to be associated with atherosclerosis and inflammatory disease, in patients with hypertension.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Mouse
Mouse
Product By Gene ID 356
Alternate Names
  • APTL
  • Fas ligand
  • Fas antigen ligand
  • CD178 antigen
  • Apoptosis antigen ligand
  • tumor necrosis factor ligand superfamily member 6
  • tumor necrosis factor (ligand) superfamily, member 6
  • apoptosis (APO-1) antigen ligand 1
  • CD178
  • TNFSF6FasL
  • FASLCD95 ligand
  • APT1LG1CD95L
  • CD95-L
  • Fas ligand (TNF superfamily, member 6)

Research Areas for Fas Ligand/TNFSF6

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Apoptosis
Cancer
Diabetes Research
Immunology

Bioinformatics Tool for Fas Ligand/TNFSF6

Discover related pathways, diseases and genes to Fas Ligand/TNFSF6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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