MMR/CD206/Mannose Receptor Products

MMR/CD206/Mannose Receptor An ...
MMR/CD206/Mannose Receptor Antibod...
Species: Mu
Applications: WB, Flow, IHC, CyTOF-ready
Host: Goat Polyclonal
MMR/CD206/Mannose Receptor An ...
MMR/CD206/Mannose Receptor Antibod...
Species: Hu
Applications: WB, Simple Western, IHC, ICC/IF
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Formulation Catalog # Availability Price  
MMR/CD206/Mannose Receptor An ...
MMR/CD206/Mannose Receptor Antibod...
Species: Hu, Fu, Pm
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Human MMR/CD206/Mannose Recep ...
Human MMR/CD206/Mannose Receptor E...
Species: Hu
Applications: ELISA
Rat MMR/CD206/Mannose Recepto ...
Rat MMR/CD206/Mannose Receptor ELI...
Species: Rt
Applications: ELISA
Recombinant Human MMR/CD206 P ...
Recombinant Human MMR/CD206 Protein
Species: Hu
Applications: Binding Activity
Formulation Catalog # Availability Price  
Recombinant Mouse MMR/CD206 P ...
Recombinant Mouse MMR/CD206 Protein
Species: Mu
Applications: Binding Activity
Formulation Catalog # Availability Price  
Recombinant Rat MMR/CD206 Pro ...
Recombinant Rat MMR/CD206 Protein, CF
Species: Rt
Applications: Bioactivity
Formulation Catalog # Availability Price  


The Mannose Receptor (MR), a member of the vertebrate C-type lectin family, is a pattern recognition receptor that is involved in both innate and adaptive immunity. The 180 kDa transmembrane protein consists of 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail.The structure is shared by the family of multi lectin mannose receptors: the phospholipase A2-receptor, DEC 205 and the novel C-type lectin receptor (mannose receptor X). The MR recognises a wide range of gram positive and gram negative bacteria, yeasts, parasites and mycobacteria. The MR has also been shown to bind and internalize tissue-type plasminogen activator. MR's are present on monocytes and dendritic cells (DC) and are presumed to play a role in innate and adaptive immunity, the latter via processing by DC. The expression of MR as observed in immunohistology is present on tissue macrophages, dendritic cells, a subpopulation of endothelial cells, Kupffer cells and sperm cells. The expression of MR on monocytes increases during culture and can be enhanced by cytokines such as IFN-gamma. Labeling of MR expressing monocytes/macrophages increases with prolonged incubation time probably due to internalization of the MR-antibody-complex. The antibody 15-2 prevents binding of glycoproteins including t-PA to MR. Detection of the MR with anti-MR monoclonal antibody 15-2 can substitute staining for mannose containing probes as labeled mannosylated BSA, a technique which is more cumbersome and less specific.


Entrez Human
Uniprot Human
Product By Gene ID 4360
Alternate Names
  • CD206
  • CLEC13Dmacrophage mannose receptor 1
  • C-type lectin domain family 13 member D
  • mannose receptor, C type 1
  • MMRCD206 antigen

Research Areas for MMR/CD206/Mannose Receptor

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Innate Immunity
Signal Transduction

PTMs for MMR/CD206/Mannose Receptor

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Bioinformatics Tool for MMR/CD206/Mannose Receptor

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