CyTOF-reported, ELISA(Cap), ICFlow, NeutHost:
WB, CyTOF-ready, ICC, ICFlowHost:
Applications: Func, PAGE
Applications: RNAi, RNAi SP
IL-5 (T cell replacing factor (TRF), eosinophil differentiation factor (EDF)) is a hematopoietic growth factor that stimulates the proliferation, differentiation and activation of eosinophils. It is produced by mast cells, T cells and eosinophils and has an important role in activating cell-mediated immunity following parasitic infections. It belongs to the same cytokine family as IL-3 and GM-CSF. The biologically active IL-5 consists of an antiparallel homodimer linked by disulfide bonds. Human and murine IL-5 are 70% identical at the amino acid level and show species cross-reactivity. IL-5 exerts its effects on target cells by binding to specific cell surface receptors.
|Product By Gene ID
- Eosinophil differentiation factor
- TRFB cell differentiation factor I
- IL-5T-cell replacing factor
- B-cell differentiation factor I
- interleukin 5 (colony-stimulating factor, eosinophil)
Bioinformatics Tool for IL-5
Discover related pathways, diseases and genes to IL-5. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.