CCL18/PARC Products

Description

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses. [provided by RefSeq]

Bioinformatics

Entrez	6362 Human
Uniprot	NP_002979 Human
Product By Gene ID	6362
Alternate Names	Alternative macrophage activation-associated CC chemokine 1 AMAC-1 AMAC1CC chemokine ligand 18 AMAC-1Small-inducible cytokine A18 CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) CKb7 DC-CK1 DC-CK1CC chemokine PARC DCCK1Macrophage inflammatory protein 4 Dendritic cell chemokine 1 MIP4 MIP-4 MIP-4C-C motif chemokine 18 PARC PARCPulmonary and activation-regulated chemokine SCYA18chemokine (C-C), dendritic small inducible cytokine A18 small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary andactivation-regulated

Research Areas for CCL18/PARC

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Cancer