TNFAIP8 Antibody

Western Blot: TNFAIP8 Antibody [H00025816-B01P] - Analysis of TNFAIP8 expression in transfected 293T cell line by TNFAIP8 polyclonal antibody. Lane 1: TNFAIP8 transfected lysate(20.9 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

TNFAIP8 Antibody Summary

• Immunogen: TNFAIP8 (NP_055165.1, 1 a.a. - 190 a.a.) full-length human protein. MAVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKMLDEENI
• Specificity: TNFAIP8 - tumor necrosis factor, alpha-induced protein 8,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: TNFAIP8
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. Immunohistochemistry was reported in scientific literature.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TNFAIP8 Antibody

• GG2-1
• Head and neck tumor and metastasis-related protein
• MDC-3.13TNF-induced protein GG2-1
• NDED
• NF-kappa-B-inducible DED-containing protein
• SCC-S2SCCS2
• TNF alpha-induced protein 8
• tumor necrosis factor alpha-induced protein 8
• tumor necrosis factor, alpha-induced protein 8

Background

Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TNFAIP8 Antibody (H00025816-B01P)(1)

Publication using H00025816-B01P

• Schuster C, Malinowsky K, Liebmann S et al. Antibody validation by combining immunohistochemistry and protein extraction from formalin-fixed paraffin-embedded tissues. Histopathology. 2012-05-01 [PMID: 22393911] (WB, IF/IHC, Human)
  
  Details:
  cIAP2/BIRC3 (IMG-5718): Formalin-fixed paraffin-embedded human colon carcinoma tissue was used in WB & IHC (paraffin), Tables 1, 2, S1, S2, Fig 3F. cIAP2 was primarily detected at 34 kDa in WB, which is an cIAP2 alternate variant form. Note: The purpose o

Bioinformatics

• Gene Symbol: TNFAIP8
• Entrez:
  • 25816(Human)
• Uniprot:
  • NP_055165.1(Human)