TMPRSS3 Antibody

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Western Blot: TMPRSS3 Antibody [NB100-77342] - (0.1ug/ml) staining of A431 cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

TMPRSS3 Antibody Summary

Immunogen
Peptide with sequence C-EKIVYHSKYKPKR corresponding to internal region according to NP_076927.1, NP_115777.1, NP_115780.1, NP_115781.1.
Epitope
EKIVYHSKYKPKR
Specificity
This antibody is expected to recognise all four reported isoforms (NP_076927.1; NP_115777.1; NP_115780.1; NP_115781.1)
Predicted Species
Mouse (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
TMPRSS3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 0.3 ug/ml
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Approx. 48 kDa band observed in A431 lysates (calculated MW of 49.4 kDa band according to NP_076927.1).
Publications
Read Publication using NB100-77342.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TMPRSS3 Antibody

  • DFNB10
  • DFNB8
  • EC 3.4.21
  • EC 3.4.21.-
  • gene similar to transmembrane serine protease10ECHOS1Serine protease TADG-12
  • serine protease TADG12
  • TADG12
  • transmembrane protease serine 3
  • transmembrane protease, serine 3
  • Tumor-associated differentially-expressed gene 12 protein

Background

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Four alternatively spliced variants have been described, two of which encode identical products.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TMPRSS3 Antibody (NB100-77342)(1)

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Video Protocols

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Bioinformatics

Gene Symbol TMPRSS3
Entrez
Uniprot