TCR V delta 2 Antibody (B6) - BSA Free

Flow Cytometry: TCR V delta 2 Antibody (B6) [NBP3-11706] - Separation of human TCR Vdelta2 positive lymphocytes (red-filled) from human TCR Vdelta2 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human TCR Vdelta2 (B6) purified antibody (concentration in sample 0,3 ug/ml, GAM APC).

Flow Cytometry: TCR V delta 2 Antibody (B6) [NBP3-11706] - Surface staining pattern of human peripheral whole blood stained using anti-human TCR Vdelta2 (B6) purified antibody (concentration in sample 0,3 ug/ml, GAM APC).

Flow Cytometry: TCR V delta 2 Antibody (B6) [NBP3-11706] - Multicolor surface staining pattern of human lymphocytes using anti-human TCR Vdelta2 (B6) purified antibody (concentration in sample 0,3 ug/ml, GAM APC) and anti-human CD3 (UCHT1) PE antibody (4 ul reagent / 100 ul of peripheral whole blood).

• Reactivity: Hu
• Applications: Flow
• Clone: B6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

TCR V delta 2 Antibody (B6) - BSA Free Summary

• Description: Novus Biologicals Mouse TCR V delta 2 Antibody (B6) - BSA Free (NBP3-11706) is a monoclonal antibody validated for use in Flow. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Human recombinant TCR Vdelta2
• Specificity: The mouse monoclonal antibody B6 recognizes an extracellular epitope of human TCR V delta 2, which is expressed on the majority of gamma/delta T cells.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: TRDV2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1-4 ug/ml

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Phosphate buffered saline (PBS), pH 7.4
• Preservative: 15mM Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for TCR V delta 2 Antibody (B6) - BSA Free

• hDV102S1

Background

TCR V delta 2 is a variant of TCR delta chain, that is present on a major subset of human gamma/delta T cells. TCR Vgamma9/Vdelta2 (or Vgamma2/Vdelta2) T cells are able to recognize and kill various tumor cells, as this receptor heterodimer binds to certain phosphoantigens, expressed by tumors. They can recognize these antigens in an MHC-unrestricted manner. Similarly to NK cells, Vdelta2 T cells express MHC I receptors and killer Ig-like receptors, that are involved in tumor recognition and cytolysis. The potently cytotoxic subset of them is identified by cell surface expression of polysialyated CD56.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TRDV2