RGS17 Antibody - Azide and BSA Free

Product Discontinued

RGS17 Antibody - Azide and BSA Free Summary

• Immunogen: Synthetic peptide: LTVRNEERGE NAGRPTHTTK MESIQVLEEC QNPTAEEVLS WSQNFDKMMK APAGRNLFRE, corresponding to amino acids 41-100 of RGS17.
• Localization: Membrane
• Specificity: RGS17
• Clonality: Polyclonal
• Host: Chicken
• Gene: RGS17
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:200 - 1:500

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (88%). Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for RGS17 Antibody - Azide and BSA Free

• hRGS17
• regulator of G-protein signaling 17
• regulator of G-protein signalling 17
• RGS-17
• RGSZ2

Background

This protein is a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RGS17
• Entrez:
  • 26575(Human)
  • 56533(Mouse)
  • 308118(Rat)
• Uniprot:
  • NP_036551.3(Human)