WB: Experiments gave bands at approx. 18 kDa band and 40 kDa band in rat brain lysate after 0.3ug/ml antibody staining. The appearance of a band with much higher molecular weight corresponds to earlier findings in scientific literature with different antibodies (PMID: 11535606). This protein has a calculated MW of 16.9 kDa band according to mouse NP_058590.1 and 16.8 kDa band according to rat NP_113833.1.
Read Publications using NBP1-20966 in the following applications:
Predicted cross-reactivity based on sequence identity: Human, Mouse.
Alternate Names for RAMP1 Antibody
calcitonin receptor-like receptor activity modifying protein 1
Calcitonin-receptor-like receptor activity-modifying protein 1
CRLR activity-modifying protein 1
receptor (calcitonin) activity modifying protein 1
receptor (G protein-coupled) activity modifying protein 1
receptor activity modifying protein 1
receptor activity-modifying protein 1
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.