Rab1A Antibody (3F10)

Western Blot: Rab1A Antibody (3F10) [H00005861-M07A] - Detection against Immunogen (36.63 KDa) .

Product Discontinued

Rab1A Antibody (3F10) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: RAB1A (NP_004152.1, 106 a.a. ~ 204 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGC
• Specificity: RAB1A - RAB1A, member RAS oncogene family (3F10)
• Isotype: IgM Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: RAB1A
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Rab1A Antibody (3F10)

• DKFZp564B163
• member RAS oncogene family
• RAB1
• Rab1A
• RAB1A, member RAS oncogene family
• ras-related protein Rab-1A

Background

The small GTPase RAB1 controls vesicle traffic from the endoplasmic reticulum (ER) to the Golgi apparatus. Rab1 belongs to the Ras superfamily of GTPases that cycle between inactive GDP-bound and active GTP-bound forms (Allan et al., 2000 [PubMed 10903204]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Rab1A Antibody (H00005861-M07A)(4)

Publications using H00005861-M07A

• Thomas JD, Zhang YJ, Wei YH et al. Rab1A Is an mTORC1 Activator and a Colorectal Oncogene. Cancer Cell. 2014-01-01 [PMID: 25446900]
• Kicka S, Shen Z, Annesley SJ et al. The LRRK2-related Roco kinase Roco2 is regulated by Rab1A and controls the actin cytoskeleton. Mol Biol Cell. 2011-05-05 [PMID: 21551065]
• Halbert D, Domenyuk V, Spetzler D et al. Aptamers and uses thereof United States Patent Application US 9958448 B2 2018-01-01
• Thomas JD, Zhang YJ, Wei YH et al. Rab1A Is an mTORC1 Activator and a Colorectal Oncogene. Cancer Cell 2016-08-02 [PMID: 27479033]

Bioinformatics

• Gene Symbol: RAB1A
• Entrez:
  • 5861(Human)
• Uniprot:
  • NP_004152.1(Human)