PTH1R/PTHR1 Antibody (734630) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 734630
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

PTH1R/PTHR1 Antibody (734630) [CoraFluor™ 1] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human PTH1R/PTHR1
  Tyr23-Met189
  Accession # Q03431
• Specificity: Detects human PTH1R/PTHR1 in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PTH1R
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for PTH1R/PTHR1 Antibody (734630) [CoraFluor™ 1]

• MGC138426
• parathyroid hormone 1 receptorMGC138452
• parathyroid hormone/parathyroid hormone-related peptide receptor
• parathyroid hormone/parathyroid hormone-related protein receptor
• PFE
• PTH/PTHr receptor
• PTH/PTHrP type I receptor
• PTH1 receptor
• PTH1R
• PTHR
• PTHR1
• PTHRPTHR1parathyroid hormone receptor 1
• seven transmembrane helix receptor

Background

PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR. PTHR1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus. ESTs have been isolated from B-cell/lung/testis, brain, breast, fetus, heart, heart/melanocyte/uterus, kidney, liver/spleen, lung, placenta, and testis libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTH1R