PTGER4/EP4 Antibody

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NBP1-84834] - Staining of human fallopian tube shows weak membranous positivity in glandular cells.

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NBP1-84834] - Staining of human duodenum shows strong memranous positivity in glandular cells

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NBP1-84834] - Staining of human fallopian tube shows weak membranous positivty in glandular cells.

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NBP1-84834] - Staining of human kidney shows strong membranous positivity in cells in tubules.

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NBP1-84834] - Staining of human stomach shows moderate membranous positivity in glanular cells.

Product Discontinued

PTGER4/EP4 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: QLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQEDTTSLRTLRISETSDSSQG
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTGER4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (83%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for PTGER4/EP4 Antibody

• EP4
• EP4R
• MGC126583
• PGE receptor EP4 subtype
• PGE receptor, EP4 subtype
• PGE2 receptor EP4 subtype
• prostaglandin E receptor 4 (subtype EP4)
• prostaglandin E2 receptor EP4 subtype
• Prostanoid EP4 receptor
• PTGER2
• PTGER4

Background

Prostaglandin E receptor EP4 is a Prostanoid Receptor with a relaxing effect on smooth muscle. It may play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. EP4 has been reported to be expressed in blood, colon, immune tissue, intestine, kidney, lung, ovary, skin, and uterus. ESTs have been isolated from a wide range of human tissue libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTGER4