Protocadherin-1 Antibody (648127) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: Flow, CyTOF-ready, ICC/IF
• Clone: 648127
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

Protocadherin-1 Antibody (648127) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
• Immunogen: E. coli-derived recombinant human Protocadherin-1
  Thr58-Asn162
  Accession # Q08174
• Specificity: Detects human Protocadherin-1 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PCDH1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for Protocadherin-1 Antibody (648127) [CoraFluor™ 1]

• cadherin-like 1
• Cadherin-like protein 1
• FLJ53887
• MGC45991
• PC42
• PC42PCDH42
• PCDH1
• PCDH42
• protocadherin 1 (cadherin-like 1)
• protocadherin 1
• protocadherin 42
• Protocadherin1
• Protocadherin-1
• protocadherin-42

Background

PCDH1 belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PCDH1