Protocadherin-1 Antibody (648127) [Biotin]

• Reactivity: Hu
• Applications: Flow, CyTOF-ready, ICC/IF
• Clone: 648127
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Biotin

Protocadherin-1 Antibody (648127) [Biotin] Summary

• Immunogen: E. coli-derived recombinant human Protocadherin-1
  Thr58-Asn162
  Accession # Q08174
• Specificity: Detects human Protocadherin-1 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PCDH1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for Protocadherin-1 Antibody (648127) [Biotin]

• cadherin-like 1
• Cadherin-like protein 1
• FLJ53887
• MGC45991
• PC42
• PC42PCDH42
• PCDH1
• PCDH42
• protocadherin 1 (cadherin-like 1)
• protocadherin 1
• protocadherin 42
• Protocadherin1
• Protocadherin-1
• protocadherin-42

Background

PCDH1 belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PCDH1