PP14C Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

PP14C Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human PP14C
  
  

  Source: E.coli

  Amino Acid Sequence: IDIDDLLDADSDEERASKLQEALVDCY

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: PPP1R14C
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10-100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP3-25061It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for PP14C Recombinant Protein Antigen

• CPI17-like
• KEPIPKC-potentiated PP1 inhibitory protein
• kinase C-enhanced PP1 inhibitor
• Kinase-enhanced PP1 inhibitor
• NY-BR-81
• protein phosphatase 1 regulatory subunit 14C
• protein phosphatase 1, regulatory (inhibitor) subunit 14C
• Serologically defined breast cancer antigen NY-BR-81

Background

Inhibitor of PPP1CA. Has over 600-fold higher inhibitory activity when phosphorylated, creating a molecularswitch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPP1R14C