PDE3A Antibody

Immunohistochemistry-Paraffin: PDE3A Antibody [NB110-40462] - Analysis of anti-PDE3A antibody with human testis.

Product Discontinued

PDE3A Antibody Summary

• Immunogen: Synthetic 19 aa peptide from near N-terminus of human PDE3A.
• Epitope: near N-terminus of human
• Specificity: Human PDE3A. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except EDN3 (58%).
• Predicted Species: Primate (94%), Monkey (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PDE3A
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (94%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 0.27 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PDE3A Antibody

• CGI-PDE A
• cGI-PDE
• cGMP-inhibited 3'-5'-cyclic phosphodiesterase A
• cyclic GMP inhibited phosphodiesterase A
• Cyclic GMP-inhibited phosphodiesterase A
• EC 3.1.4
• EC 3.1.4.17
• PDE3A
• phosphodiesterase 3A, cGMP-inhibited

Background

Phosphodiesterase 3A is a cGMP inhibited, cAMP/cGMP dual-specific phosphodiesterase. PDE3A has been implicated in male erectile dysfunction, mammalian oocyte maturation, platelet function, vascular smooth muscle function, and salivary gland tumors. Three alternatively spliced transcripts have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PDE3A
• Entrez:
  • 5139(Human)