Recombinant Human NQO-2 Protein Summary
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-231 of Human NQO-2
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAGKKVLIVY AHQEPKSFNG SLKNVAVDEL SRQGCTVTVS DLYAMNFEPR ATDKDITGTL SNPEVFNYGV ETHEAYKQRS LASDITDEQK KVREADLVIF QFPLYWFSVP AILKGWMDRV LCQGFAFDIP GFYDSGLLQG KLALLSVTTG GTAEMYTKTG VNGDSRYFLW PLQHGTLHFC GFKVLAPQIS FAPEIASEEE RKGMVAAWSQ RLQTIWKEEP IPCTAHWHFG Q
| Protein/Peptide Type
>95% pure by SDS-PAGE
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT
>95% pure by SDS-PAGE
Alternate Names for Recombinant Human NQO-2 Protein
- EC 22.214.171.124
- NAD(P)H dehydrogenase, quinone 2
- NAD(P)H menadione oxidoreductase 2, dioxin-inducible
- NRH dehydrogenase [quinone] 2
- NRH:quinone oxidoreductase 2
- Quinone Reductase 2
- ribosyldihydronicotinamide dehydrogenase [quinone]
- ribosyldihydronicotinamide dehydrogenase
NQO2 is a member of the NAD(P)H dehydrogenase (quinone). The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. It is flavoproteins that catalyze the metabolic detoxification of quinones and their derivatives to hydroquinones. This detoxification process protects cells against quinone-induced oxidative stress, cytotoxicity and mutagenicity. Recombinant human NQO2 protein was expressed in E.coli and purified by using conventional chromatography techniques.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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