NDUFS8 Antibody

Western Blot: NDUFS8 Antibody [H00004728-B01P] - Analysis of NDUFS8 expression in transfected 293T cell line by NDUFS8 polyclonal antibody. Lane 1: NDUFS8 transfected lysate(23.1 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

NDUFS8 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: NDUFS8 (NP_002487.1, 1 a.a. - 210 a.a.) full-length human protein. MRCLTTPMLLRALAQAARAGPPGGRSLHSSAVAATYKYVNMQDPEMDMKSVTDRAARTLLWTELFRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR
• Specificity: NDUFS8 - NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: NDUFS8
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for NDUFS8 Antibody

• CI-23k
• CI23KD
• CI-23kD
• complex I 23kDa subunit
• Complex I-23kD
• EC 1.6.5.3
• EC 1.6.99.3
• EC 1.6.99.5
• NADH dehydrogenase (ubiquinone) Fe-S protein 8 (23kD) (NADH-coenzyme Qreductase)
• NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Qreductase)
• NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
• NADH-ubiquinone oxidoreductase 23 kDa subunit
• TYKY subunit
• TYKY

Background

NDUFS8 (NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)) is a subunit of NADH. Mutations in NDUFS8 have been linked to Leigh syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for NDUFS8 Antibody (H00004728-B01P)(1)

Publication using H00004728-B01P

• Cheng CW, Kuo CY, Fan CC et al. Overexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species. Cell Death Dis. 2013-06-20 [PMID: 23788038]

Bioinformatics

• Gene Symbol: NDUFS8
• Entrez:
  • 4728(Human)
• Uniprot:
  • NP_002487.1(Human)